When pain lives in one knee, one shoulder, or one nerve, the medication can go there too. Mediglen compounds topical and transdermal pain preparations from your prescriber's formula, combining agents such as diclofenac, gabapentin, cyclobenzaprine, lidocaine, and ketamine into a single cream that treats the site with less systemic exposure than oral therapy.
Oral pain medication has to travel through the whole body to reach one joint. That journey is where most side effects happen: the stomach irritation of anti-inflammatories, the drowsiness of muscle relaxants and nerve agents, the kidney load of long-term NSAID use.
A compounded topical takes the shorter route. Applied at the painful site, it concentrates the medication where the problem is. For patients who cannot tolerate oral NSAIDs, who take many other medications, or whose pain has more than one mechanism, this is often the practical answer.
The second advantage is combination. Pain is rarely one thing: inflammation, nerve irritation, and muscle spasm usually arrive together. Compounding lets the prescriber address each mechanism in a single preparation rather than three separate products.
Each formula is built to the prescription, in the base that suits the site: cream, transdermal gel, ointment, or lotion.
A sample of established formulas from our compounding formulary. Every preparation is made to your prescriber's exact specification; strengths and combinations are routinely adjusted.
| Use | Formula | Active ingredients |
|---|---|---|
| Arthritis and joint pain | MPR465 | Diclofenac sodium 10% topical gel |
| Osteoarthritis | MPR982 | Cyclobenzaprine 2%, diclofenac sodium 5%, glucosamine sulfate 10% cream |
| Neuropathic pain | MPR450v2 | Diclofenac sodium 2%, gabapentin 6% cream |
| Severe neuropathic pain | MPR550v3 | Gabapentin 6%, ketamine 9.2%, ketoprofen 8% cream |
| Neuropathic pain | MPR990 | Amitriptyline 2%, gabapentin 5% cream |
| Nerve pain with spasm | MPR988 | Cyclobenzaprine 2%, gabapentin 6%, lidocaine 10% cream |
| Muscle spasm | MPR828v2 | Cyclobenzaprine 5%, lidocaine 5% cream |
| Spasm with inflammation | MPR060v2 | Baclofen 2%, diclofenac sodium 3% cream |
| Shingles pain | MPR986 | Acyclovir 5%, lidocaine 2% gel |
| Gout flares | MPR410v4 | Guaifenesin 10%, indomethacin 10%, lidocaine 2% transdermal gel |
| Migraine | MPR386v4 | Indomethacin 10% transdermal gel |
| Plantar fasciitis | MPR991 | Ketoprofen 10%, piroxicam 3% cream |
| Anal fissures | MPR748 | Lidocaine 1.5%, nifedipine 0.3% rectal ointment |
| Pre-procedure numbing | MPR749v2 | Benzocaine 20%, lidocaine 6%, tetracaine 4% paste |
Yes. Every compounded pain preparation is made from a prescription written by your physician, nurse practitioner, or dentist. If you are not sure what to ask for, our pharmacists can suggest formulation options for your prescriber to review.
A topical or transdermal preparation delivers medication at the painful site, so a knee, shoulder, or nerve area gets treated without the whole body being exposed. For many patients this means meaningful relief with less of the stomach, kidney, or drowsiness burden that oral therapy can carry.
Yes. Combining agents that work by different mechanisms, for example an anti-inflammatory with a nerve agent and a muscle relaxant, is one of the main reasons prescribers turn to compounding. One jar replaces several products.
Common prescriptions cover osteoarthritis and joint pain, neuropathic pain including diabetic neuropathy and post-shingles pain, muscle spasm and sports injuries, plantar fasciitis, gout flares, migraine, and anorectal conditions such as fissures.
Compounded preparations are not Health Canada-approved manufactured products. They are individually prepared for one patient from a prescription, under College of Pharmacists of BC oversight and NAPRA non-sterile compounding standards.
Most pain compounds are prepared within one to two business days, with same-day service often possible for established formulas. Pickup on The High Street or free Tri-Cities delivery.